Indicatios:

Cefuroxime powder for solution for injection or infusion is indicated for the treatment of infections listed below in adults and children, including neonates (from birth).

• Community acquired pneumonia

• Acute exacerbations of chronic bronchitis

• Complicated urinary tract infections, including pyelonephritis

• Soft-tissue infections: cellulitis, erysipelas and wound infections

• Intra-abdominal infections

• Prophylaxis against infection in gastrointestinal (including oesophageal), orthopaedic, cardiovascular, and gynaecological surgery (including caesarean section)

In the treatment and prevention of infections in which it is very likely that anaerobic organisms will be encountered, cefuroxime should be administered with additional appropriate antibacterial agents.

Dosage and administration:

Cefuroxime should be administered by intravenous injection over a period of 3 to 5 minutes directly into a vein or via a drip tube or infusion over 30 to 60 minutes, or by deep intramuscular injection.

Contraindications:

Hypersensitivity to cefuroxime or to any of the excipients.

Patients with known hypersensitivity to cephalosporin antibiotics.

History of severe hypersensitivity (e.g. anaphylactic reaction) to any other type of beta-lactam antibacterial agent (penicillins, monobactams and carbapenems).

Storage:

Protect from light. Before reconstitution do not store above 25°C. After reconstitution the product may be stored at 2°C-8°C (in a refrigerator) for up to 24 hours